Purpose: The purpose of this study was to investigate the effects of home-and-workplace combined
exercise on physical function, depression, and work-related disability in patients with ankylosing
spondylitis.
Methods: This study adopted a non-randomized quasi-experimental design. Fifty-two patients were
recruited: home-and-workplace combined exercise (n = 17), home exercise (n = 18), and control group
(n = 17).
Results: The home-and-workplace combined exercise group showed improvement in spinal mobility and
pulmonary function and significantly lower absenteeism and overwork impact than the home-exercise
group and control group. The home-and-workplace combined exercise and home exercise groups
showed a higher level of activity improvement than the control group.
Conclusion: home-and-workplace combined exercise can be recommended to patients with ankylosing
spondylitis to enhance their physical function, including spinal mobility and pulmonary function, and
reduce work-related disability.