Purpose: The aim of the study was to determine the effectiveness of dignity therapy for end-of-life
patients with cancer.
Methods: This study used a quasi-experimental study design with a nonrandomized controlled trial.
Dignity therapy was used as an intervention in the experimental group, and general visit was used in the
control group. Thirty end-of-life patients with cancer were recruited, with 16 in the experimental group
and 14 in the control group. Outcome variables were the participants' dignity, demoralization, and
depression. Measurements were taken at the following time points: pre-test (before intervention), post-test
1 (the 7th day), and post-test 2 (the 14th day). The effectiveness of the intervention in the two
groups was analyzed using the generalized estimating equation, with the p value set to be less than .05.
Results: After dignity therapy, the end-of-life patients with cancer reflected increased dignity significantly
[β = -37.08, standard error (SE) = 7.43, Wald χ2 = 24.94, p < .001], whereas demoralization
(β = -39.55, SE = 6.42,Wald χ2 = 37.95, p < .001) and depression (β = -12.01, SE = 2.17,Wald χ2 = 30.71,
p < .001) were both reduced significantly.
Conclusion: Clinical nurses could be adopting dignity therapy to relieve psychological distress and
improve spiritual need in end-of-life patients with cancer. Future studies might be expanded to
looking at patients vis-a-vis end-of-life patients without cancer to improve their psychological
distress. These results provide reference data for the care of end-of-life patients with cancer for
nursing professionals.