Purpose: The purpose of this study was to develop website-based learning contents to activate voluntary
monitoring and reporting of adverse drug reactions (ADRs) for clinical nurses and to verify their
effectiveness.
Method: Using a quasi-experimental control group pretest-posttest design with random allocation, a
total of 60 nurses with more than 1 year of clinical experience were recruited from a university hospital
in Seoul, Korea. A website was developed that provides learning contents including real cases and the
latest drug-related knowledge, as well as video lectures. Knowledge on ADR monitoring, self-efficacy,
ADR practice behavior, and medication performance ability were measured at 2 weeks after intervention.
A small notebook for monitoring ADRs of nurses was given to the control group. Data were analyzed
using descriptive statistics, the chi-squared test, and the independent t test using SPSS Statistics Software
Version 21.0.
Results: The scores of ADR monitoring knowledge, self-efficacy, and ADR monitoring practice in the
experimental group significantly increased after the intervention compared with the control group
(p < .05). However, there was no significant difference between the two groups in medication performance
ability related to ADR monitoring.
Conclusion: To spread a safety culture in which voluntary ADR monitoring and reporting is activated, it is
necessary for clinical nurses to share and communicate ADR-related information and real cases through
an open website.