Purpose: This study was aimed to investigate the incidence and risk factors of dyslipidemia
in women with menopause using a Korean community-based longitudinal study. Methods:
The subjects were 245 postmenopause women without dyslipidemia who participated in the
Ansan-Ansung cohort study from 2001–2002 (baseline) to 2015–2016 (seventh follow-up
visit) were followed. The dyslipidemia incidence was measured as incidence proportion (%)
and incidence rate per 100 person-years. Predictors of developing dyslipidemia were analyzed
with Cox’s proportional hazard model. Results: The incidence of new dyslipidemia during the
follow-up period was 78.4% (192 patients), and 11.9 per 100 person-years. Mean duration from
menopause to developing dyslipidemia was 5.3 years in new dyslipidemia cases.
Triglyceride/high density lipoprotein (TG/HDL-C) ratio at baseline (Hazard ratio=2.20, 95%
confidence interval=1.39-3.48) was independently associated with developing dyslipidemia.
Conclusion: Dyslipidemia occurs very frequently in postmenopausal women, especially within
5 years after menopause. Therefore, efforts are required to prevent dyslipidemia from
immediately after menopause, particularly, in women with a high TG/HDL-C ratio at
menopause.