Purpose: This study identified the epidemiological characteristics, including the size and major strains, of
carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) and CP-CRE-related factors
by comparing the characteristics of patients in the CP-CRE and non-CP-CRE groups and the CP-CRE
and non-CRE groups.
Methods: This secondary data analysis study included 24 patients in the CP-CRE group, 113 patients in
the non-CP-CRE group, and 113 in the non-CRE group. The size and type of CP-CRE were analyzed in
terms of frequency and percentage, and CP-CRE risk factors were identified using multiple logistic
regression analysis.
Results: The rate of CP-CRE positivity among patients with CRE was 17.5%, and the most common
causative organism in the CP-CRE group was Klebsiella pneumoniae (81.8%). There were no significant
differences between patients in the CP-CRE and non-CP-CRE groups. When compared with the non-CRE
group, the isolation of multidrug-resistant organisms except for CRE, particularly vancomycin-resistant
Enterococcus, was confirmed as a major risk factor.
Conclusion: To prevent CP-CRE acquisition, patients with multidrug-resistant organisms require treatment
with more thorough adherence to CRE prevention and management guidelines.